PROGYNOVA | ZYDUS PHARMA

Description

PROGYNOVA contains Estradiol Valerate, a synthetic form of the natural estrogen hormone used in hormone replacement therapy (HRT). It is primarily prescribed to manage symptoms of estrogen deficiency in women, particularly during menopause. PROGYNOVA helps regulate hormonal balance, alleviate menopausal symptoms, and maintain reproductive health. It is manufactured by Zydus Pharma, a trusted name in global pharmaceuticals.

💡 What is Estradiol Valerate?

Estradiol Valerate is a prodrug of estradiol — the most potent natural estrogen. Once ingested, it is converted into estradiol in the body. It helps replace the estrogen that the body no longer makes after menopause. This hormone plays a crucial role in regulating the menstrual cycle, supporting reproductive health, and maintaining bone density in women.

🩺 Medical Uses of PROGYNOVA

• Hormone Replacement Therapy (HRT): Manages hot flashes, night sweats, mood swings, and vaginal dryness associated with menopause.

• Estrogen Deficiency: Treats symptoms of low estrogen due to ovarian failure or removal of ovaries.

• Menstrual Disorders: Used in certain cases to regulate menstrual cycles or manage amenorrhea.

• Transgender Hormone Therapy: Often part of feminizing hormone therapy in transgender women.

• Prevention of Osteoporosis: Helps maintain bone density in postmenopausal women.

💊 How to Use PROGYNOVA

• Administered orally with water; typically taken once daily.

• Follow the dosing schedule as prescribed by your doctor.

• Do not chew or crush the tablet.

• Consistency is important — take at the same time each day.

📏 Dosage Instructions

• Typical Dosage: 1 mg to 2 mg per day, adjusted based on medical condition and response.

• Course Duration: Determined by the prescribing physician based on individual needs.

• Follow-up: Regular medical check-ups are advised to monitor hormone levels and treatment response.

Do not self-medicate or adjust dosage without consulting your doctor.

⚠️ Side Effects

Common Side Effects:

• Nausea or vomiting

• Headache

• Breast tenderness

• Bloating

• Mood changes

Serious Side Effects (Seek immediate medical help):

• Chest pain or shortness of breath

• Sudden vision changes

• Leg swelling or pain (possible blood clot)

• Unusual vaginal bleeding

• Signs of liver dysfunction (e.g., yellowing of skin/eyes)

🛑 Precautions

Before using PROGYNOVA, inform your doctor if you have:

• A history of blood clots or stroke

• Liver or kidney disease

• Breast or uterine cancer

• Uncontrolled hypertension

• Migraine headaches

• Diabetes

Not recommended during pregnancy or breastfeeding.

💊 Drug Interactions

PROGYNOVA may interact with:

• Anticonvulsants (e.g., phenytoin, carbamazepine)

• Certain antibiotics or antifungals

• Anticoagulants

• St. John’s Wort

• Hormonal contraceptives

Always inform your healthcare provider about all medications and supplements you’re taking.

🌡️ Storage Guidelines

• Store at room temperature below 25°C.

• Keep away from moisture and direct sunlight.

• Do not use expired medication.

• Keep out of reach of children.

❌ Who Should Not Use PROGYNOVA

• Women with a history of hormone-sensitive cancers

• Those with active blood clots or clotting disorders

• Individuals with unexplained vaginal bleeding

• Pregnant or breastfeeding women

• People allergic to estradiol valerate or any component of the tablet

💪 Key Benefits

• Effectively relieves menopausal and estrogen-deficiency symptoms

• Maintains bone health and prevents osteoporosis

• Supports hormonal balance and reproductive wellness

• Useful in transgender HRT protocols

⚠️ Warnings & Safety Information

• Not intended for use in men or children

• Long-term use requires regular monitoring due to potential cancer risk

• Should be used at the lowest effective dose for the shortest duration

• Regular breast and pelvic exams are recommended during therapy

📦 Packaging & Availability

• Supplied in blister packs of 28 tablets

• Available in 1 mg and 2 mg strengths

• Prescription required for purchase

• Manufactured under GMP standards by Zydus Pharma

❓ Frequently Asked Questions (FAQs)

Q1. Can PROGYNOVA be used for birth control?
➡️ No. PROGYNOVA is not a contraceptive and should not be used for birth control.

Q2. How soon will I notice the effects of PROGYNOVA?
➡️ Relief from symptoms usually begins within a few weeks, but full benefits may take a few months.

Q3. Is it safe to use PROGYNOVA long-term?
➡️ Long-term use should be carefully monitored by a healthcare provider due to associated risks.

Q4. Can men use PROGYNOVA for hormone therapy?
➡️ It may be used under medical supervision in male-to-female transgender hormone therapy.

Q5. What should I do if I miss a dose?
➡️ Take the missed dose as soon as possible. If it’s close to the next dose, skip it — do not double up.